右心室功能指数和血小板参数用于早期预测支气管肺功能障碍的价值:一项回顾性研究
Tianzi Li1, Bei Xia1, Suixin Liang2
1Department of Ultrasound, Shenzhen Children's Hospital of China Medical University, Shenzhen, Guangdong, China.
BMC pediatrics
|June 11, 2024
概括
早期的回声心脏指数和血小板参数可以识别高风险的早产婴儿的支气管肺功能失调 (BPD). 三环状平面缩外流 (TAPSE) 和心肌性能右心室指数 (RIMP),结合血小板计数和平均血小板体积 (MPV),改善了BPD的预测.
科学领域:
- 新生儿医学 新生儿医学
- 儿童心脏病学 儿童心脏病学
- 关键的护理关键的护理
背景情况:
- 支气管肺功能障碍症 (BPD) 是早产婴儿的一个重大并发症.
- 早期识别患有BPD风险的婴儿对于及时干预至关重要.
- 右心室功能和血小板参数是潜在的早期指标.
研究的目的:
- 评估早期回声心脏学指数对右心室功能与血小板 (PLT) 参数相结合的预测价值,用于早产婴儿的BPD.
- 为了确定BPD发展的独立风险因素.
主要方法:
- 对早产婴儿 (GA < 32 周) 进入新生儿重症监护室的回顾性研究.
- 在DOL 1,7和14上对右心室功能进行心声评估 (TAPSE,RIMP).
- 在DOL 1,7和14上测量PLT参数 (PLT计数,MPV,PCT,PDW).
- 多变量逻辑回归和ROC曲线分析以确定预测值.
主要成果:
- 与非BPD婴儿相比,患有BPD的婴儿在DOL 14上显示出较高的RIMP和较低的TAPSE.
- 在DOL 1.上,BPD婴儿的PLT计数较低,MPV较高.
- 妊娠年龄,机械通风持续时间,PLT计数,MPV,TAPSE和RIMP是BPD的独立风险因素.
- 对右心室功能指数和PLT参数的联合使用改善了BPD预测 (AUC = 0.846).
结论:
- 三环状平面缩外流 (TAPSE) 和心肌性能右心室指数 (RIMP) 是BPD风险的有价值的早期心声学标志物.
- 血小板计数和平均血小板体积 (MPV) 也有助于早期BPD风险评估.
- 结合TAPSE,RIMP,PLT计数和MPV,可以更好地识别患BPD风险较高的早产婴儿.
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