在异形性内高血压中的正静性半面
Madison M Patrick1, Galen K Postma, Rachel A H Bielling
1Department of Clinical Sciences, Florida State University College of Medicine (MMP, RB, CGM), Tallahassee, Florida; Department of Clinical Sciences, Florida State University (GP, BT), Tallahassee, Florida; and Department of Neuro-Ophthalmology (ARC), Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
概括
异常性内高血压 (IIH) 可以导致罕见的半面 (HFS). 一个新的理论表明,IIH中的HFS与压力变化有关,而不仅仅是高内压力 (ICP).
科学领域:
- 神经学 神经学
- 眼科医生 眼科 眼科
- 神经外科 神经外科
背景情况:
- 半面 (Hemifacial spasm,简称HFS) 是一种罕见的异常性内高血压 (IIH) 的症状.
- 在IIH中,直立式诱导的HFS在腰部穿刺 (LP) 之前是一个未报告的呈现.
- 本案例系列回顾了IIH中的HFS,并提出了发生的新机制.
研究的目的:
- 描述两种异常的异常性内高血压 (IIH) 病例,呈现出半面 (HFS).
- 审查IIH中关于HFS的现有文献.
- 建议在IIH开发HFS的新机制.
主要方法:
- 介绍了两例IIH和HFS女性的病例报告.
- 诊断方法包括神经成像和腰部穿刺 (LP) 来测量开口压力 (OP) 和脑脊液 (CSF) 组成部分.
- 治疗涉及乙胺,并监测症状的缓解.
主要成果:
- 两位患者都经历了HFS,在一个病例中,症状发生在静态状态下.
- 开启压力高 (46cmH2O和32cmH2O) 与正常的CSF.
- 在这两位患者中,乙胺有效地消除了HFS和其他IIH症状.
结论:
- 在站立时出现高压并在LP后持续存在的情况与传统的高内压力 (ICP) 机制相矛盾.
- 一个拟议的机制涉及显著的ICP波动,由于IIH的低内合规性.
- 这个理论解释了HFS的发展与ICP变化的*程度*有关,而不是静态的高ICP.
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