立陶宛和瑞典的他类药物使用和缺血性心脏病死亡率的趋势,2000-2020年
Indre Treciokiene1, Kamile Daukintyte1, Paul Hjemdahl2
1Pharmacy and Pharmacology Centre, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Upsala journal of medical sciences
|June 12, 2024
概括
在立陶宛和瑞典,他类药物的使用增加,但仅在瑞典,缺血性心脏病死亡率下降. 这凸显了需要改善立陶宛的他类药物处方和心血管风险管理.
科学领域:
- 心血管医学 心血管医学
- 公共卫生 公共卫生
- 药物经济学 药物经济学
背景情况:
- 心血管疾病仍然是全球主要的死亡原因.
- 类药物被广泛处方用于管理高脂血症和降低心血管风险.
- 对他类药物的使用和缺血性心脏病 (IHD) 死亡率趋势的比较研究对于公共卫生战略至关重要.
研究的目的:
- 为了比较2000年至2020年立陶宛和瑞典之间的他类药物使用和IHD死亡率的趋势.
- 评估这两个国家的他类药物使用和IHD死亡率之间的相关性.
主要方法:
- 生态研究设计分析时间趋势.
- 关于他类药物使用 (DDD/TID) 和IHD死亡率 (每10万人口) 的数据从国家数据库中收集.
- 使用斯皮尔曼等级和皮尔森系数进行相关性分析.
主要成果:
- 在2000年至2020年期间,立陶宛和瑞典的他类药物使用量显著增加.
- 瑞典的IHD死亡率大幅下降,但仍然很高,在立陶宛增加.
- 在瑞典 (r = -0.993) 观察到他类药物使用与IHD死亡率之间的反相关性,而在立陶宛 (rs = 0.871) 发现了正相关性.
结论:
- 尽管他类药物的使用增加,立陶宛的IHD死亡率上升,与瑞典的下降形成鲜明对比.
- 在他类药物的强度和处方实践的差异可能会影响结果.
- 在立陶宛,需要优化心血管风险因素管理和他类药物的使用.
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