在中期复发性复发性硬化症患者中,关于疾病修改治疗选择的决策冲突
Julia Sabin1, Elisa Salas2, Jesús Martín-Martínez3
1Department of Neurology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Patient preference and adherence
|June 12, 2024
概括
在选择治疗的中期复发性复发性多发性硬化症 (RRMS) 患者中,决策冲突很常见. 提高MS的知识和自我管理可以减少这种冲突.
科学领域:
- 神经学 神经学
- 临床心理学 临床心理学
背景情况:
- 共同决策对于多发性硬化症 (MS) 管理至关重要,因为疾病的不确定性和许多治疗选择.
- 患有复发性复发性多发性硬化症 (RRMS) 的患者在疾病修饰疗法 (DMT) 方面面临复杂的选择.
研究的目的:
- 评估中期RRMS患者关于DMT选择的决策冲突.
- 在这个患者群体中确定与决策冲突相关的因素.
主要方法:
- 一项多中心的非干预性研究,涉及201名成年患者,其RRMS持续时间为3-8年.
- 利用决策冲突量表和各种患者报告的结果指标.
- 进行多变量逻辑回归分析以确定相关因素.
主要成果:
- 33.3%的患者报告了决策冲突.
- 决策冲突与较低的MS知识,较高的疾病不确定性,焦虑,抑郁,疲劳和较差的生活质量有关.
- 缺乏决策冲突与增加的MS知识,更好的自我管理和更少的遗憾相关.
结论:
- 在选择DMT的中期RRMS患者中,决策冲突很普遍.
- 诸如MS知识和自我管理能力等因素影响决策冲突.
- 有针对性的干预措施可以帮助患者更好地了解他们的病情,并提高自我管理技能.
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