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自闭症适应安全计划的可行性和可接受性:外部试点随机对照试验

Jacqui Rodgers¹, Sarah Cassidy², Mirabel Pelton^1,3

¹Population Health Sciences Institute, Newcastle University, NE1 7RU, UK.

EClinicalMedicine

|June 12, 2024

概括

自伤高风险的自闭症成年人可以使用自闭症适应安全计划 (AASP). 一项试点试验表明,AASP是可行的和可接受的,为更大规模的自杀预防自闭症患者研究铺平了道路.

科学领域:

神经发育障碍神经发育障碍
心理健康研究心理健康研究
临床心理学临床心理学

背景情况:

自闭症患者面临自我伤害和自杀的高风险.
现有的自杀预防干预措施并不适合自闭症患者.
对于这个人口群体,有必要采取基于证据的干预措施.

研究的目的:

试验自闭症适应安全计划 (AASP) 的可行性随机对照试验 (RCT).
评估AASP的可行性和可接受性,以减少自闭症成年人自我伤害和自杀风险.
为未来最终试验的设计提供信息.

主要方法:

在英国进行了一项随机,双臂,受控试验.
招募了53名自闭症成年人,并随机分配到与AASP或没有AASP的通常护理.
AASP交付的可行性,可接受性,保留性和忠实性是主要结果,在6个月内进行评估.

主要成果:

试点试验符合进展标准,表明未来最终试验的可行性.
68%的参与者对AASP感到满意,41%的人认为它是可用的.
在两个试验组中都观察到优秀的保留率和结果测量完成率.

结论:

自闭症适应性安全计划 (AASP) 是一个可行的和可接受的干预方案,为自闭症成年人提供自我伤害和自杀的风险.
该研究为评估AASP的临床和成本效益的最终RCT提供了坚实的基础.
未来的研究应该调查在常规临床实践中AASP的实施.

关键词:

自闭症自闭症自闭症自闭症成人自闭症成年人安全规划安全规划自己伤害的自我伤害自杀自杀的自杀是自杀的自杀.

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