相关实验视频
Updated: Jun 24, 2025

05:56
A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
Published on: February 20, 2021
2.1K
[患有败血症的患者体甲状腺疾病综合征的相关因素]
Yuanyuan Zeng1, Yun Xie1, Daonan Chen1
1Department of Emergency And Critical Care, Shanghai General Hospital of Nanjing Medical University, Shanghai 201620, China.
概括
甲状腺疾病综合征 (ESS) 影响28.2%的败血症患者,表明预后较差. 前素,IL-6,CRP,SAA和APTT是关键的危险因素,而FT3显示出预测败血症死亡率的潜力.
科学领域:
- 内分泌学 在内分泌学.
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
背景情况:
- 乙甲状腺病综合征 (ESS) 是一种常见的内分泌障碍,严重病患者,特别是败血症患者常见.
- 了解败血症中ESS的患病率和风险因素对于改善患者的治疗结果至关重要.
研究的目的:
- 为了确定ESS在败血症患者的患病率.
- 确定影响败血症ESS发展的因素.
- 在败血症患者中评估ESS和自由三铁氨酸 (FT3) 的预后价值.
主要方法:
- 在2017年1月至2023年1月期间入住上海一家医院的365名败血症患者的回顾性分析.
- 患者被分为ESS和非ESS组.
- 用多变量逻辑回归来确定风险因素,并比较30天生存率. 对FT3.3进行了接收器操作特征 (ROC) 曲线分析.
主要成果:
- 败血症患者中ESS的患病率为28.2%.
- 患有ESS的患者表现出较高的败血症严重性得分 (APACHE II,SOFA) 和升高的炎症标志物 (CRP,PCT,SAA,IL-6).
- 对于ESS的独立风险因素包括PCT,IL-6,CRP,SAA和APTT,而HDL-C是一个保护因素. 在ESS组中,30天的生存率明显较低. 在预测死亡率方面,FT3表现出高准确度 (AUC 0.924).
结论:
- 在败血症患者中,ESS是普遍存在的,并且与严重程度和死亡率的增加有关.
- 炎症标志物和凝血参数是败血症中ESS的重要预测因素.
- 血清FT3水平可以作为预测败血症患者死亡率的宝贵生物标志物.
相关概念视频
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K
Factors Affecting Body Temperature
4.1K
As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may include:
Factors may include:
4.1K
Autoimmune Disorders
417
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
417
Irritable Bowel Syndrome I: Introduction
268
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
268
Pneumonia III: Complications and Assessment
200
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
200

