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Updated: Jun 24, 2025

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
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连续或间歇性β- 乳酸抗生素输液在患有败血症的重症患者:BLING III随机临床试验

Joel M Dulhunty1,2,3, Stephen J Brett4,5, Jan J De Waele6

  • 1Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

JAMA
|June 12, 2024
PubMed
概括

与间歇注射相比,持续注射β- 乳酸抗生素治疗败血症并没有显著降低90天的死亡率. 然而,持续输液显示了临床治愈率改善的趋势.

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相关概念视频

One-Compartment Model: IV Infusion01:09

One-Compartment Model: IV Infusion

Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
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