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Updated: Jun 24, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
09:03

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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革命性的GPCR-联体预测:DeepGPCR具有高精度药物发现实验验证

Haiping Zhang1, Hongjie Fan2, Jixia Wang2,3

  • 1Faculty of Synthetic Biology and Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, No. 1068 Xueyuan Boulevard, Nanshan District, Shenzhen 518055, Guangdong Province, China.

Briefings in bioinformatics
|June 12, 2024
PubMed
概括

新的深度学习模型,DeepGPCR_BC和DeepGPCR_RG,使用非结构数据准确预测与G蛋白合受体 (GPCRs) 的药物相互作用. 这些模型允许有效的虚拟选用于针对GPCRs的药物发现.

关键词:
这是一个GLP-1RR.在GPCR中,GPCR是指GPCR.在 GPR35 中使用.药物查对药物进行查.图表 卷积网络 卷积网络

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