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在儿科手术镇静期间的手术前氧化和手术氧化:使用模式和与干预措施的关联
Joyce Li1, Baruch Krauss1, Michael C Monuteaux1
1Division of Emergency Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.
在儿科镇静中,手术前氧化和手术后氧化并没有减少呼吸道,呼吸或循环干预. 这些简单的策略虽然可能有益,但在这项大型研究中,它们对不良事件没有显著的影响.
科学领域:
- 麻醉学 麻醉学
- 儿科镇静剂 儿科镇静剂
- 患者安全 患者安全
背景情况:
- 建议进行手术前氧化和手术后氧化,以减少镇静期间的不良事件.
- 了解这些氧化策略的实践模式和有效性,对于优化儿科镇静方案至关重要.
研究的目的:
- 在儿科镇静中描述手术前氧化和手术后氧化的实践模式.
- 测试假设这些氧化策略可以降低呼吸道/呼吸/循环干预的风险.
主要方法:
- 对85,599例儿科镇静治疗 (2020年4月至2023年7月) 的回顾性,多中心,横截面研究.
- 来自儿科镇静研究联盟数据库的数据.
- 用于评估干预措施的风险差异的治疗权重的逆概率.
主要成果:
- 50.5%的患者接受了手术前的氧化; 61.0%接受了手术后的氧化.
- 在程序前氧化 (RD -0.06%) 或程序性氧化 (RD -1.07%) 的整体干预中没有统计学上显著的差异.
- 两种策略的置信区间包括零,表明没有显著的影响.
结论:
- 预防性程序前氧化和程序性氧化与呼吸道/呼吸/循环干预措施的减少无关.
- 目前的证据不支持这些氧化策略在减轻儿科镇静期间不良事件的显著益处.
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