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Updated: Jun 24, 2025

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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暂时的PP2A SIP复合体局部化到线性SPBs用于SIN抑制,仅由Csc1 FHA域介导

Alaina H Willet1, Liping Ren1, Lesley A Turner1

  • 1Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37240.

Molecular biology of the cell
|June 12, 2024
PubMed
概括

该SIP复合体通过其FHA域与SPB结,抑制了正确细胞分裂的分离开始网络 (SIN). 构成性局部化是致命的,但突变会破坏抑制,揭示精确的时空控制机制.

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