关于在胃模型中使用数值分析的审查
Xinying Liu1, David F Fletcher1, Gail M Bornhorst2,3
1School of Chemical and Biomolecular Engineering, University of Sydney, Sydney, New South Wales, Australia.
Journal of food science
|June 12, 2024
概括
数字胃模型提供了对食物消化的洞察力. 这篇综述涵盖了二十年的计算建模,突出了对胃过程的更深入理解和更健康的食品开发的进展和未来方向.
科学领域:
- 生物医学工程 生物医学工程
- 计算流体动力学的流体动力学.
- 胃肠病学 胃肠病学
背景情况:
- 食物消化对于人类健康至关重要.
- 在体外模型在研究复杂的胃过程方面存在局限性.
- 数字方法提供了对胃流和化学的全面了解.
研究的目的:
- 为了回顾过去二十年来开发的数值胃模型.
- 讨论用于计算建模的必要胃生理参数.
- 为了比较胃消化模型中使用的计算方法.
主要方法:
- 计算流体动力学 (CFD) 和固体力学方法的审查.
- 讨论胃的几何结构,运动性,排空和分泌物.
- 对挑战,局限性和未来研究领域的分析.
主要成果:
- 在模拟胃壁运动的胃液流动方面取得了进展.
- 目前的模型缺乏全面实施复杂的食物分解和化学消化.
- 计算能力的进步将彻底改变数值方法.
结论:
- 数字化胃模型对理解胃消化有很大的潜力.
- 需要进一步的研究,以纳入复杂的食物分解和化学过程.
- 改进的建模将有助于开发更健康的食品.
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