术前认知功能作为癌症手术中术后妄想的危险因素:系统性审查和元分析
Hesam A Varpaei1, Lorraine B Robbins1, Kousha Farhadi2
1College of Nursing Michigan State University, East Lansing, Michigan, USA.
Journal of surgical oncology
|June 12, 2024
概括
手术前的认知功能显著预测了癌症手术患者的手术后妄想 (POD) 风险. 手术前较低的认知分数与患POD的可能性更高有关.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 神经科学是一个神经科学.
背景情况:
- 手术后妄 (POD) 是癌症手术后的一个常见并发症.
- 导致POD的因素包括麻醉,手术持续时间和先前存在的认知障碍.
- 癌症手术后POD中术前认知功能的特定作用需要进一步澄清.
研究的目的:
- 确定术前认知功能与癌症手术后POD的可能性之间的关系.
- 综合现有关于手术前认知评估和癌症患者POD发病率的证据.
主要方法:
- 按照PRISMA指南进行了系统审查和随机效应元分析.
- 包括原始的英语文章,评估手术前的认知功能和固体瘤癌症手术后的POD.
- 使用标准化平均差异 (SMD) 和赔率比率 (OR) 分析了数据.
主要成果:
- 整体POD发病率在8.7%至50.9%之间.
- 在手术前,较低的迷你精神状态检查 (MMSE) 评分与较高的POD风险相关 (SMD = -0.84).
- 手术前的认知功能障碍显著预测了POD发生 (OR = 5.17).
结论:
- 手术前的认知功能是固体瘤癌症手术后POD的独立和显著预测因素.
- 在癌症手术前进行认知评估可能有助于识别POD高风险患者.
- 进一步的研究可以探索有针对性的干预措施,以根据手术前的认知状态来减轻POD风险.
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