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高分辨率基质特异性分析SARS-CoV-2 Mpro;与SARS-CoV Mpro进行比较

Rasha M Yaghi1, Collin L Andrews1, Dennis C Wylie2

  • 1Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States of America.

ACS chemical biology
|June 12, 2024
PubMed
概括

SARS-CoV-2 主蛋白酶 (Mpro) 对于病毒成熟至关重要,并且是Paxlovid的目标. 我们的研究显示,SARS-CoV-2和SARS-CoV Mpro具有相同的基质特异性,有助于新的抑制剂设计.

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