来自人类细胞外囊泡的非编码RNA yREX3通过一种新的基因甲基化机制,通过巨细胞介导心脏保护

Alessandra Ciullo1, Liang Li1, Chang Li1

  • 1Cedars-Sinai Medical Center, Smidt Heart Institute, 8700 Beverly Blvd, 1090 Davis Bldg, Los Angeles, CA 90048, USA.

PubMed
概括

心脏球衍生的细胞细胞外囊泡含有YRNA,可以防止心脏病发作. YRNAs使用DNA甲基化来通过沉默巨细胞中的Pick1基因来减少损伤.

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