在多中心研究中的结核性淋巴腺炎的诊断方法
Ercan Yenilmez1, Duygu Özakınsel2, Adem Köse3
1Health Sciences University, Hamidiye Faculty of Medicine, Fatih Sultan Mehmet Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, İstanbul, Turkiye.
Journal of infection in developing countries
|June 12, 2024
概括
结核淋巴腺炎 (TBLN) 在土耳其很常见. 这项研究确定了区分TBLN与淋巴腺病变的其他原因的关键因素,有助于临床诊断.
科学领域:
- 传染性疾病 传染性疾病
- 临床医学 临床医学
- 公共卫生 公共卫生
背景情况:
- 结核性淋巴腺炎 (TBLN) 是土耳其成年人患外周淋巴腺病的主要传染性原因.
- 区分TBLN与非结核性淋巴腺炎 (NTBLN) 对于有效的患者管理至关重要.
研究的目的:
- 确定人口统计学,临床和实验室指标,使TBLN与成年人中的NTBLN有所区别.
- 在研究成年人群中确定淋巴腺病的主要病因.
主要方法:
- 一个多中心,嵌套的病例控制研究,涉及812名成年患者.
- 纳入标准:18岁以上患有外围淋巴腺病的患者接受淋巴结活检 (2010年1月至2021年3月).
主要成果:
- 最常见的诊断是TBLN (53.69%).
- 与较高的TBLN发病率相关的因素:女性性别,红细胞沉积率升高,阳性净化蛋白衍生物 (PPD) 试验,阳性干扰素释测试 (IGRA).
- 与较低的TBLN发病率相关的因素:泛型,双边,关或 inguinal 淋巴腺病变,肝病巨变,病巨变,白细胞病变和中度升高的C反应蛋白.
结论:
- 确定TBLN的预测变量对于优化诊断策略至关重要.
- 这项研究为在土耳其管理成人淋巴腺病的临床医生提供了宝贵的见解.
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