COVID-19对结核病通知的影响
Talita Antunes Antoniolli Pontes1, Fernando Fernandez-Llimos2, Astrid Wiens3
1Universidade Federal do Paraná, Programa de Pós-Graduação em Assistência Farmacêutica, Curitiba, Paraná, Brazil.
Revista do Instituto de Medicina Tropical de Sao Paulo
|June 12, 2024
概括
2020年和2021年,COVID-19大流行导致圣保罗州的结核病 (TB) 通知显著下降. 这种对结核病报告的影响凸显了潜在的低诊断挑战.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 随着COVID-19大流行,全球医疗保健系统受到压力,可能会破坏基本的疾病监测.
- 结核病 (TB) 控制计划可能已经间接受到大流行病对医疗保健的压倒性影响的影响.
研究的目的:
- 分析COVID-19流行病对圣保罗州结核病 (TB) 通知的影响.
- 量化大流行期间结核病例报告的变化.
主要方法:
- 从TBweb数据库 (2015年1月至2022年12月) 获得的177103个TB事件病例通知的回顾性分析.
- 间断时间序列 (ITS) 分析与贝叶斯因果影响评估,使用流行病声明作为中断事件.
主要成果:
- 2020年结核病通知的显著下降率为13%,而2021年则下降了9%.
- 观察到的结核病通知的变化与区域人口密度或地理区域没有显著的关联.
- 减少的统计学意义在2022年之前就消失了.
结论:
- 在2020年和2021年期间,COVID-19大流行大大减少了圣保罗州的结核病通知.
- 对结核病诊断不足的进一步研究至关重要,以了解报告不足对结核病发病率和死亡率的长期影响.
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