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在心脏手术后的手术内葡萄糖和损伤:一项回顾性队列研究

Yuyang Zhang¹, Shuang Cai¹, Xinglong Xiong²

¹Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, China.

The Journal of surgical research

|June 12, 2024

概括

高的手术内血糖水平增加了急性损伤 (AKI) 的风险,在心脏手术后. 保持葡萄糖低于127.8 mg/dL可能有助于预防AKI.

科学领域:

腎臟病學 (nephrology) 是一種醫學專業.
心脏病学心脏病学
内分泌学在内分泌学.

背景情况:

急性损伤 (AKI) 是在心脏手术后的常见并发症.
以前的研究表明,血糖和术后的AKI之间存在联系.
关于心脏外科手术中的特定手术内血糖值的数据有限.

研究的目的:

为了研究在手术期间血糖峰值和术后AKI之间的关联.
为了确定与AKI风险相关的关键的手术内葡萄糖度切断值.

主要方法:

追溯性,单中心研究,包括3375名接受心脏手术的成年患者.
主要结局:术后AKI的发生率.
多变量物流分析,使用受限立方线来评估葡萄糖-AKI关系.

主要成果:

AKI的整体发病率为18.0%.
患有AKI的患者表现出明显更高的峰值手术内葡萄糖水平.
经过调整后的分析显示,高峰性手术内血糖 (aOR 1.08,95% CI 1.03-1.12) 增加了AKI风险.
在葡萄糖水平超过127.8 mg/dL (7.1 mmol/L) 后,AKI风险开始显著增加.

结论:

术后血糖升高与术后AKI的风险更高有关.
对于接受心脏手术的患者,保持峰值手术内葡萄糖低于127.8 mg/dL (7.1 mmol/L) 可能会减轻AKI风险.

关键词:

急性损伤是什么?急性损伤是什么?心脏外科手术是一项心脏手术.截止值是指截止值是指截止值.在手术期间的血糖水平.在-机上.

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