基本金属之间的关联,坚持健康的生活方式行为,以及脚-手腕指数
Xiya Qin1, Gaojie Fan1, Qing Liu1
1Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, HangKong Road 13, Wuhan, Hubei 430030, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
适当摄入,铁和等必需金属,再加上健康的生活方式,对于预防外围动脉疾病至关重要. 这项研究强调了这些金属和生活方式因素在维持血管健康方面的保护作用.
科学领域:
- 环境健康 环境健康
- 心血管健康 心血管健康
- 营养科学 营养科学
背景情况:
- 脚-手臂指数 (ABI) 是对外围动脉疾病 (PAD) 的一个关键的非侵入性指标.
- 此外,ABI还可以作为未来心血管事件的重要预测指标.
- 了解影响ABI的因素对于心血管风险评估至关重要.
研究的目的:
- 调查基本金属 (单独和组合) 与ABI之间的联系.
- 评估必需金属和健康的生活方式对ABI的协同效应.
- 确定有助于血管健康结果的特定必需金属.
主要方法:
- 利用了来自武汉通吉医院招募的2865名参与者的数据.
- 使用感应合血质谱法测量了必需金属的尿度.
- 使用通用线性回归和WQS回归模型来分析关联.
主要成果:
- 在ABI和尿 (Cr),铁 (Fe) 和 (Co) 水平之间发现了积极的关联.
- 一种基本金属的混合物与ABI显示出显著的积极关系,Cr和Co是主要贡献者.
- 健康的生活方式与较高的Cr,Fe和Co四分位数相结合,与不利条件相比,显著增加了ABI.
结论:
- 足够的必需金属摄入量,特别是Cr,Fe和Co,在预防PAD方面发挥着至关重要的作用.
- 将健康的生活方式行为与足够的基本金属状态相结合,对于心血管保护至关重要.
- 研究结果支持营养状况和生活方式在管理血管健康方面的重要性.
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