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在患有严重急性呼吸道感染的重症患者中进行非侵入性通风
Ghaida Jabri1,2,3, Farah Alotaibi4, Amjad M Ahmed1,5,2
1King Saud bin Abdulaziz University for Health Sciences, College of Medicine, Riyadh, Saudi Arabia.
Respiratory care
|June 12, 2024
概括
与侵入性通风相比,在严重急性呼吸道感染中使用非侵入性通风 (NIV) 与90天死亡率较低有关. 需要进一步的研究来优化对NIV.患者的选择.
科学领域:
- 关键护理医学 关键护理医学
- 呼吸系统医学 呼吸系统医学
- 肺部疾病 肺部疾病
背景情况:
- 严重急性呼吸道感染 (SARI) 具有显著的死亡风险.
- 呼吸系统支持对于治疗SARI患者急性呼吸衰竭至关重要.
- 将非侵入性通风 (NIV) 和侵入性通风 (IV) 进行比较对于优化SARI治疗至关重要.
研究的目的:
- 为了评估非侵入性通风 (NIV) 和侵入性通风 (IV) 之间的关联,关于严重急性呼吸道感染 (SARI) 患者的死亡率.
- 为了比较最初接受NIV和IV治疗的SARI患者之间的90天死亡率.
- 在SARI中确定与不同通风策略相关的潜在好处和风险.
主要方法:
- 追溯式,多中心研究设计.
- 包括2012年9月至2018年6月期间接受呼吸器支持的SARI患者.
- 倾向性得分调整以比较NIV和IV组之间的90天死亡率.
主要成果:
- 总共分析了383名SARI患者,其中NIV组189名,IV组194名.
- 与IV组 (39.7%) 相比,NIV组的原始90天死亡率明显较低 (22.2%).
- 在倾向性得分调整后,NIV使用与90天死亡率显著降低相关 (OR0.54,95% CI 0.38-0.76).
结论:
- 非侵入性通风 (NIV) 经常用于急性呼吸系统衰竭的严重急性呼吸系统感染 (SARI).
- 在SARI患者中,NIV证明了与90天死亡率降低的关联.
- 高的NIV失败率需要进一步的研究,以优化患者选择和早期失败识别.
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