在老年和年轻的密码性缺血性中风患者之间比较的专利卵巢孔的形态特征
Mitsutaka Nakashima1, Yoichi Takaya1, Rie Nakayama1
1Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
概括
高风险的专利卵孔 (PFO) 形态在加密性中风 (CS) 的老年患者中很常见. 这些发现与年轻患者相似,为PFO关闭决定提供了信息.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 专利卵孔 (PFO) 形态影响密码性中风 (CS) 风险和透导管关闭决策.
- 关于老年CS患者PFO形态的数据有限,大多数研究集中在年轻人群中.
- 了解老年CS患者的PFO特征对于适当的治疗选择至关重要.
研究的目的:
- 为了比较高风险PFO形态的患病率在老年 (≥60岁) 和年轻 (<60岁) 患者与CS史.
- 评估这些年龄段的隔膜失调和PFO相关的中风致病概率.
主要方法:
- 经食道心声学用于评估169名CS和PFO患者的PFO形态.
- 患者被分为两个年龄组:≥60岁和<60岁.
- 使用了PFO相关的中风病因概率分类系统.
主要成果:
- 老年患者 (≥60岁) 与年轻患者相比,心房隔膜动脉瘤的患病率显著更高.
- 在年龄组之间的大右向左分流,长PFO道,尤斯塔希亚门或奇亚里网络的流行中没有发现显著差异.
- 在60岁以上的患者中, Septal malalignment的发生频率更高,近90%的患者被归类为"可能"的CS风险.
结论:
- 高风险的PFO形态在CS的老年患者中普遍存在,类似于年轻的队列.
- 年龄不会显著改变某些PFO特征的流行率,如分流或道.
- 这些发现支持考虑在老年CS患者中关闭PFO,这些患者具有已确定的高风险形态.
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