人类视觉白物质轨迹在健康和疾病中的轨迹测量
Hiromasa Takemura1,2,3, John A Kruper4, Toshikazu Miyata1,3
1Division of Sensory and Cognitive Brain Mapping, Department of System Neuroscience, National Institute for Physiological Sciences, Okazaki, Aichi, Japan.
概括
扩散权重核磁共振 (dMRI) 导管测量分析视觉白质道. 测量与视觉功能和疾病相关,为老龄化社会提供了洞察力.
科学领域:
- 神经成像是一种神经成像.
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
背景情况:
- 扩散权重MRI (dMRI) 提供了对大脑组织特性的非侵入性见解.
- 轨道测量使用dMRI分析大脑网络中的远程连接.
- 视觉白质谱对于处理环境信息和日常活动至关重要.
研究的目的:
- 审查基于dMRI的通道测量方法来分析视觉白质道.
- 探索视觉白质性质,视觉功能和疾病之间的关系.
- 确定面临的挑战和未来的方向,以临床整合的轨道测量.
主要方法:
- 关于dMRI轨道测量分析管道的概述:数据采集,模型拟合,轨道图,轨道识别和物业概况.
- 对特定视觉通道的dMRI分析的综述:视神经,视通道,光辐射,大子和垂直尾囊.
- 解剖学知识的综合和最近的导管测量发现.
主要成果:
- 视觉白质道的测量对各种疾病敏感.
- 轨道测量结果与感知能力相关.
- 经过dMRI通道测量,可以评估视觉系统的健康状况.
结论:
- 视觉白质的轨道测量对于了解与衰老相关的视觉系统疾病至关重要.
- 对于视觉障碍的临床应用,dMRI通道测量方法显示出有前途.
- 解决协议间的变化是将通道测量纳入临床实践的关键.
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