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Updated: Jun 24, 2025

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人类胃癌的进展和稳定ATG2B通过RNF5结合,由自相关的CircDHX8促进

Guanxin Wei1, Xiang Chen1, Tuo Ruan1

  • 1Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Cell death & disease
|June 12, 2024
PubMed
概括

循环RNA circDHX8通过增强自促进胃癌 (GC) 的进展. 它通过抑制其降解来增加ATG2B蛋白水平,促进细胞增殖和GC中的入侵. 这项研究揭示了GC恶性瘤中circDHX8的新型机制.

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