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相关概念视频

Eccentric Loading01:16

Eccentric Loading

353
Eccentric loading is a crucial concept in the study of structural engineering and mechanics, particularly when analyzing the stability and stress distribution in columns. Unlike centric loading, where the force is applied along the centroidal axis, causing uniform compression, eccentric loading occurs when a force is applied off-center. This off-center application introduces not only direct compressive stress but also bending stress, significantly influencing the column's behavior under...
353

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静态负荷作为术后并发症的预测因子,乳腺癌患者.

J C Chen1, Mohamed I Elsaid2,3,4, Demond Handley2,3

  • 1Division of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA.

NPJ breast cancer
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概括

累积压力,以全静电负荷 (AL) 衡量,与乳腺癌患者的术后并发症 (POC) 的增加有关. 更高的AL显著提高了手术后发展POC的风险.

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科学领域:

  • 在瘤学瘤学.
  • 公共卫生 公共卫生
  • 生物医学科学 生物医学科学

背景情况:

  • 静态负荷 (AL) 量化了对社会环境压力因素的累积暴露.
  • 了解影响术后并发症 (POC) 的因素对于乳腺癌手术患者的结果至关重要.

研究的目的:

  • 调查乳腺癌患者的全静态负荷 (AL) 和术后并发症 (POC) 的发生之间的关联.

主要方法:

  • 利用俄俄州癌症登记处对接受手术 (2012-2020) 的女性乳腺癌患者 (I-III阶段) 的数据.
  • 使用心血管,代谢,免疫和系统的生物标志物计算了复合AL得分.
  • 在手术后30天内使用单变量和多变量回归分析来评估AL和POC之间的关系.

主要成果:

  • 在4459名患者中,8.2%的患者经历了POC.
  • 高的AL与POC的概率增加了29% (aOR1.29).
  • 每增加一个点的AL与POC几率增加8%相关 (aOR1.08).

结论:

  • 增加的全静电负荷,反映了累积的应激暴露,与乳腺癌手术患者手术后并发症的可能性更高显著相关.
  • 这些发现突出了社会环境压力因素对外科手术结果的影响,并提出了潜在的干预目标.