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Updated: Jun 24, 2025

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KRAS和TP53共同突变预测了肺腺癌中免疫检查点阻塞的益处

Jan Budczies1,2,3, Eva Romanovsky4, Martina Kirchner4

  • 1Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany. jan.budczies@med.uni-heidelberg.de.

British journal of cancer
|June 12, 2024
PubMed
概括

同时发生的KRAS和TP53突变改善了在晚期肺癌中免疫治疗益处的预测. 这一发现在免疫治疗队列中得到了验证,为患者选择提供了更敏感的生物标志物.

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