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Updated: Jun 24, 2025

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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关于G蛋白与激素结合的G蛋白结合受体的机制性见解

Hossein Batebi1,2, Guillermo Pérez-Hernández3, Sabrina N Rahman4

  • 1Universität Leipzig, Medizinische Fakultät, Institut für Medizinische Physik und Biophysik, Leipzig, Germany.

Nature structural & molecular biology
|June 12, 2024
PubMed
概括

G-蛋白结合受体 (GPCRs) 通过释放GDP来激活G蛋白. 分子动力学揭示了受体结合如何触发Gs蛋白的结构变化,促进GDP喷射和信号传输.

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