阻塞性睡眠呼吸暂停 (OSA) 与COVID-19严重程度之间的关联
Oria Nassi-Liberman1, Bernice Oberman2, Tamar Strahl2
1Adelson School of Medicine, Ariel University, Ariel, Israel.
Journal of sleep research
|June 12, 2024
概括
阻塞性睡眠呼吸暂停增加了严重的冠状病毒疾病2019 (COVID-19) 的风险,但并没有增加死亡率. 更高的社会经济地位与严重的COVID-19和死亡风险增加有关.
科学领域:
- 医学 医学 医学 医学 医学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 和与睡眠相关的缺氧与2019年冠状病毒病 (COVID-19) 的更糟糕结果有关.
- 了解COVID-19严重性和死亡率的风险因素对于公共卫生战略至关重要.
研究的目的:
- 调查阻塞性睡眠呼吸暂停 (OSA) 与COVID-19严重程度和死亡率之间的关联.
- 检查包括社会经济地位在内的临床和人口因素对COVID-19结果的影响.
主要方法:
- 对44,275名成年患者的回顾性研究,这些患者在Omicron变种之前被诊断出COVID-19.
- 在患有和没有OSA的患者之间比较COVID-19的严重程度和死亡率.
- 多变量分析以确定严重的COVID-19和死亡率的独立风险因素.
主要成果:
- 与轻度疾病相比,OSA诊断与严重COVID-19的风险高出1.6倍.
- 在OSA患者中没有观察到COVID-19死亡率的显著增加.
- 更高的社会经济地位与严重的COVID-19风险增加相关,发病率和死亡率.
结论:
- 阻塞性睡眠呼吸暂停是严重的COVID-19的一个独立风险因素.
- 社会经济地位显著影响COVID-19的严重程度和死亡率,更高的地位带来更大的风险.
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