患有多囊性卵巢综合征的妇女的休息能量消耗

患有多囊性卵巢综合征的妇女的休息能量消耗

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Flavia Tosi¹, Federica Rosmini¹, Veronica Gremes¹

¹Endocrinology, Diabetes and Metabolism, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.

Human reproduction (Oxford, England)

|June 13, 2024

概括

患有多囊卵巢综合征 (PCOS) 的女性在调整为无脂肪质量时,其休息能量消耗 (REE) 减少. 这一发现在不同的PCOS表型和BMI类别中是一致的,表明了潜在的代谢变化.

科学领域:

内分泌学和新陈代谢学
生殖健康生殖健康
营养科学营养科学

背景情况:

肥胖在患有多囊卵巢综合征 (PCOS) 的女性中很普遍,与改变的休息能量消耗 (REE) 有潜在联系.
之前关于REE在PCOS中的研究已经产生了相互矛盾的结果,需要进一步调查.

研究的目的:

调查多囊性卵巢综合征 (PCOS) 的妇女的休息能量消耗 (REE) 是否发生变化.
为了检查REE,无脂肪质量,PCOS表型和BMI之间的关系.

主要方法:

一项病例对照研究比较了266名患有PCOS的女性和51名健康对照.
使用间接热量计测量REE;还评估了血清雌激素和胰岛素敏感性.

主要成果:

休息能量支出 (REE) 在PCOS和对照组之间相似.
然而,与无脂肪质量 (REE/FFM) 调整后的REE在患有PCOS的女性中 (31.8 kcal/kgFFM·day) 与对照组 (35.4 kcal/kgFFM·day) 相比显著较低.
在所有PCOS表型和BMI类别中观察到REE/FFM的减少,并且与年龄和PCOS状态独立相关.

结论:

患有PCOS的女性在对无脂肪质量进行校正时,表现出降低的休息能量消耗 (REE),独立于临床表现或BMI.
这种代谢变化可能会导致体重增加和PCOS的特征性代谢特征.
需要进一步的前性研究来阐明减少的REE/FFM在PCOS病理生理学和体重管理中的作用.

关键词:

在PCOS中,PCOS是PCOS.色素是一种色素.间接测热仪间接测热仪间接测热仪胰岛素敏感性胰岛素敏感性休息的能源支出休息的能源支出

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