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Updated: Jun 24, 2025

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
09:38

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

Published on: August 11, 2017

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通过MET激活的Wnt冷凝原药逆转基因驱动的NSCLC中MET介导的耐药性

Na Liu1, Xiaoqiang Zheng1,2, Jin Yan3,4

  • 1Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|June 13, 2024
PubMed
概括

在非小细胞肺癌 (NSCLC) 中,MET放大导致对EGFR向治疗的耐药性. 一种新的Wnt抑制剂,WntSI,通过向Wnt/β-catenin通路来克服这种抵抗,提供了一种新的治疗策略.

关键词:
在MET中放大放大功率.在NSCLCLC中,我们可以看到.这是一种Wnt抑制剂.药物开发是药物的发展.这是一种类.

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Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies09:29

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

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