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相关概念视频

Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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Cardiac Action Potential01:30

Cardiac Action Potential

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Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
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Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

3.2K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
3.2K
Disturbances in Heart Rhythm01:28

Disturbances in Heart Rhythm

933
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
933
Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

632
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
632
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
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Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples
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异常导电诱导心肌病:一个鲜为人知的实体.

Andrea Lalario1,2, Maddalena Rossi1,2, Valentina Allegro1,2

  • 1Centre for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department, Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI), University of Trieste, Trieste.

European heart journal supplements : journal of the European Society of Cardiology
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PubMed
概括

异常导电诱导的心肌病是异步双心室激活的结果,导致心脏功能障碍. 改善这种电动失调可以恢复心脏功能和几何,特别是在没有遗传原因的情况下.

关键词:
心脏导电障碍 心脏导电障碍心肌病心脏病变的疾病.失同症是一种失同症.遗传学 遗传学 是一个

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Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System
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Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients
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Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System
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Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients
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科学领域:

  • 心脏病学 心脏病学
  • 电子生理学 电子生理学
  • 心肌病研究研究 心肌病研究

背景情况:

  • 不同步的双心脏激活,由于条件,如左捆分支堵塞或心室节奏,损害了全球收缩性.
  • 这种异常激活导致静脉缩功能障碍和左心室重塑,定义了一个独特的心肌病组.
  • 现有疗法侧重于纠正或减轻左心室 (LV) 不同步,以逆转心脏损伤.

研究的目的:

  • 审查异常导电诱导心肌病的机制,患病率和风险因素.
  • 概述这些疾病的诊断和治疗策略.
  • 突出多式成像和多学科方法在患者管理中的作用.

主要方法:

  • 关于异常导电诱导心肌病的研究的综合文献综述.
  • 分析将电失调与心脏功能障碍联系在一起的机制.
  • 评估当前的诊断工具和治疗干预措施,包括基于设备的疗法和成像模式.

主要成果:

  • 消除或改善LV失调是主要的治疗目标,往往导致心脏功能和几何的恢复.
  • 没有遗传背景有利于更好的预后和功能恢复.
  • 多式成像和系统的病因定义对于指导治疗至关重要.

结论:

  • 异常导电诱导心肌病是一种独特的实体,其中纠正电气失调是治疗的关键.
  • 一种多学科的,以成像为指导的方法对于准确的诊断和有效的,以病因学为指导的治疗至关重要.
  • 需要进一步的研究来解决不确定性的领域和优化管理策略.