患有败血症患者在ICU获得的虚弱的危险因素:对264名患者的回顾性研究
Jiajiao Liu1, Zhaoxia Xu2, Shuhong Luo1
1Department of Critical Care Medicine, The General Hospital of Western Theater Command PLA, Chengdu, 610036, China.
Heliyon
|June 13, 2024
概括
高APACHE II分数,长时间的机械通风,保护性约束和乳酸水平升高是重症监护室获得性虚弱 (ICU-AW) 的关键危险因素. 早期识别可以帮助缓解这种常见的严重疾病并发症.
科学领域:
- 关键护理医学 关键护理医学
- 神经学 神经学
- 内部医学 内部医学
背景情况:
- 败血症是重症监护室 (ICU) 中经常出现的严重疾病.
- 败血症是发展重症监护单位获得的弱点 (ICU-AW) 的重要危险因素.
研究的目的:
- 确定和分析患有败血症的患者ICU-AW的独立风险因素.
主要方法:
- 分析了264名败血症患者的队列.
- 使用后勤回归分析来评估临床特征.
- 根据ICU-AW的存在或不存在来对患者进行分类.
主要成果:
- 多变量分析确定了APACHE II评分,机械通风持续时间,保护约束和乳酸水平作为ICU-AW的独立风险因素.
- 确定了最佳切线值:APACHE II评分>24,机械通风>5天,乳酸>2.12 mmol/L.
结论:
- 高APACHE II分数,长时间的机械通风,保护性约束和乳酸度升高是感染性患者ICU-AW的重要危险因素.
- 这些因素可以预测发展ICU-AW的可能性.
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