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Updated: Jun 24, 2025

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting
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Published on: March 1, 2019

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在尖端蛋白编码区域的APOBEC3相关突变促进了SARS-CoV-2的进化

Jiaying Shen1,2,3, Xinxin Xu4, Junyan Fan2,3,5

  • 1Tongji University School of Medicine, Tongji University, Shanghai 200120, China.

Heliyon
|June 13, 2024
PubMed
概括

在COVID-19患者中,炎症因素可能会激活APOBEC3 (阿波蛋白B mRNA编辑催化子单元类蛋白3),可能导致SARS-CoV-2的演变. APOBEC3B和USP18作为抑制病毒传播和免疫规避的治疗点具有前途.

关键词:
A3B A3B A3B A3B A3B A3B A3B A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D A3D在 APOBEC3 中,APOBEC3 是在 COVID-19 疫情中,炎症 炎症是一种炎症.编辑RNA的RNA编辑这就是SARS-CoV-2病毒.

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