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Updated: Jun 24, 2025

An In Vitro Dormancy Model of Estrogen-sensitive Breast Cancer in the Bone Marrow: A Tool for Molecular Mechanism Studies and Hypothesis Generation
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An In Vitro Dormancy Model of Estrogen-sensitive Breast Cancer in the Bone Marrow: A Tool for Molecular Mechanism Studies and Hypothesis Generation

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在TNBC中开发一种与休眠相关的ECM特征,该特征与免疫抑制瘤微环境和对MAPK抑制剂的选择性敏感性有关

Yang Dong1, Jin Bai2, Jianjun Zhou1

  • 1Research Center for Translational Medicine, Cancer Stem Cell Institute, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China.

Heliyon
|June 13, 2024
PubMed
概括

三阴性乳腺癌 (TNBC) 中的细胞休眠与特定的细胞外矩阵 (ECM) 特性有关. 准MAPK通路显示出治疗休眠TNBC细胞的前景,可能改善患者的治疗结果.

关键词:
细胞的休眠状态.化学抗药性 化学抗药性是一种抗药性.细胞外矩阵是细胞外矩阵.在 MAPK 信号通道中.三重阴性乳腺癌是什么?

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