对病毒和微生物群的抗体特征反映了过去和慢性暴露,并与衰老和炎症有关

Sergio Andreu-Sánchez1,2, Aida Ripoll-Cladellas3, Anna Culinscaia1

  • 1Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

iScience
|June 13, 2024
PubMed
概括

接触诸如细胞大脑病毒 (CMV) 和常见病毒等微生物会影响免疫系统的衰老和炎症. 对病原体的抗体反应与端粒长度相关,揭示了过去感染和生物衰老之间的联系.

相关概念视频

Humoral Immune Responses01:36

Humoral Immune Responses

Overview
72.5K
Cross-reactivity00:42

Cross-reactivity

Overview
31.0K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.6K
Antibody Actions01:26

Antibody Actions

Antibodies, or immunoglobulins, are critical players in the immune system's arsenal against invading pathogens. Produced by B cells and plasma cells, their primary role is to detect and bind to specific antigens, molecules found on the surface of pathogens like bacteria or viruses. Beyond antigen recognition, antibodies perform several vital functions that contribute to immune defense.
Neutralization
Antibodies can bind to pathogens, preventing them from infecting host cells. This process...
1.1K
Affinity and Avidity01:41

Affinity and Avidity

Overview
36.0K
Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
590