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Updated: Jun 24, 2025

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease
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MicroEXPERT:微生物组分析平台,具有交叉研究元基因组范围的关联分析功能

Pengshuo Yang1,2, Jialiang Yang3,4,5, Haixia Long6

  • 1Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Center of AI Biology, Department of Bioinformatics and Systems Biology College of Life Science and Technology, Huazhong University of Science and Technology Wuhan Hubei China.

iMeta
|June 13, 2024
PubMed
概括

MicroEXPERT是一个由五个模块组成的平台,用于分析微生物社区数据. 它促进数据管理,处理,全基因组关联研究 (MWAS),序列搜索和结果可视化,以获得全面的微生物群洞察力.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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