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在接受救援喉切除术的患者中选择性部解剖:结果,并发症和考虑因素

Nickolas A Alsup¹, Soroush Farsi¹, Sydney K Blevins¹

¹Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, USA.

|June 13, 2024

概括

先进的复发性瘤阶段预测在救援喉切除术患者中隐藏的结节疾病. 选择性部剖析没有改善结果,但如果进行,应包括侧部剖析.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
头部和部手术头部和部手术
手术瘤学手术瘤学

背景情况:

隐藏结节疾病 (OND) 是在接受救援喉切除术 (SLE) 的患者中引起关注的,临床上结节阴性 (cN0) 的部.
对OND的预测因素以及选择性部剖析 (END) 对瘤结果的影响需要进一步研究.

研究的目的:

在接受SLE的cN0患者中确定OND的预测因子.
为了比较接受END和观察管理的患者之间的瘤结果.

主要方法:

在过去的12年中,对58名患有cN0子的SLE患者进行了回顾性图表审查.
患者被分为END (n=39) 和观察 (n=19) 组.
单变异和生存分析 (日志等级测试) 用于评估OND,区域无复发生存率 (RRFS) 和疾病特异性生存率 (DSS).

主要成果:

在71个 (7%) 的部剖析标本中,有5个显示出病理结节疾病,主要是II-IV级.
先进的复发性T阶段 (rT3-rT4) 是OND的唯一显著预测因素 (p=0.017).
在END和观察组之间没有观察到术后并发症,RRFS (p=0.216) 或DSS (p=0.298) 的显著差异.

结论:

先进的复发性T阶段 (rT3-rT4) 预测在经历SLE的cn0部中OND.
如果进行END,建议进行正式的侧剖析,因为OND涉及II-IV水平.
与该队列的观察相比,END没有改善局部区域控制或存活率.

关键词:

选择性部剖析选择性部剖析隐秘节点疾病隐秘节点疾病结果就是结果.复发性复发性复发性挽救整体喉腔切除术的方法幸存率幸存率生存率

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