描述儿童的静脉外导损伤 (DIVE2研究)
Jamil Alnoor Devsi1, Vanessa Paquette2, Roxane R Carr3
1, PharmD, ACPR, is with the Department of Pharmacy, Children's & Women's Health Centre of British Columbia, Lower Mainland Pharmacy Services, and the Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia.
The Canadian journal of hospital pharmacy
|June 13, 2024
概括
儿童的外导损伤仍然很少见,常见的原因包括静脉注射液体和诸如万科米之类的药物. 大多数患者经历了轻微的结果,在本研究中没有报告抗药的不良事件.
科学领域:
- 儿科医学 儿科医学
- 临床药房 临床药房
- 患者安全 患者安全
背景情况:
- 输血,即无意中将静脉注射液体或药物注入周围组织,可能会导致严重的并发症,特别是在儿童中.
- 关于儿科外流伤害的管理和结果的数据有限,特别是关于药物抗药物的使用.
研究的目的:
- 为了确定在三级儿科中心外流伤害的发生率.
- 识别经常涉及的病原体,并评估抗药的使用和作用.
- 描述与这些伤害相关的并发症的范围.
主要方法:
- 进行了对患有外流伤害的儿科患者医疗记录的回顾性审查.
- 收集的数据包括伤害细节,管理方案和患者在12年期间的结果.
主要成果:
- 扩散的发病率为0.04%的每天患者,全方位肠道营养 (TPN) 脂质,万科米辛和IV液体是最常见的药物.
- 大多数患者,特别是新生儿和婴儿,经历了轻微的结果,没有报道抗剂的不良药物事件.
- 由于数据不完整,大量病例 (110/242) 被排除在结果分析之外.
结论:
- 在该机构的外流伤害发生率很低,具有一致的致病因子和通常温和的结果.
- 进一步的前性研究是必要的,以评估用于管理儿科患者外流伤害的抗毒剂的疗效和安全性.
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