中国草药药物的益生菌发酵研究取得了进展
Xiaoling Zhang1,2, Qin Miao1,2, Chengxue Pan1,2
1School of Pharmaceutical Sciences, Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education Zhengzhou University Zhengzhou China.
iMeta
|June 13, 2024
概括
用益生菌发酵中国草药 (CHM) 提高了它们的生物活性,降低了毒性. 这种利用微生物组和合成生物学的过程,有望实现有益化合物的经济有效的生物制造.
科学领域:
- 传统中国医药 传统中国医药
- 微生物学 微生物学
- 生物技术是生物技术.
背景情况:
- 中国草药 (CHM) 具有复杂的生物活性成分,通常具有较低的生物可用性和潜在毒性.
- 传统的CHM应用在吸收,含量和人类和动物使用的安全性方面面临挑战.
研究的目的:
- 审查益生菌发酵对CHM的优势.
- 探索发酵技术,益生菌菌株和CHM生物制造的未来方向.
主要方法:
- 审查关于CHM发酵和益生菌的现有文献.
- 分析微生物在CHM发酵过程中的作用.
- 讨论微生物组和合成生物学应用.
主要成果:
- 益生菌发酵增强了CHM的生物活性和生物可用性.
- 发酵可以降低某些CHM组件的毒性.
- 益生菌对宿主肠道微生物群和免疫功能有积极的影响.
结论:
- 益生菌发酵是一种有前途的策略,可以提高CHM的有效性和安全性.
- 像微生物组和合成生物学这样的先进工具可以优化CHM生物制造.
- 这种方法促进了从CHM中成本有效地生产有价值的生物活性天然产品.
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