在外周动脉疾病中,间歇性音与慢性肢体威胁性缺血之间的比较:一项回顾性多中心队列研究
Hye Young Woo1, Jin Hyun Joh2, Jin Mo Kang3
1Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Annals of surgical treatment and research
|June 13, 2024
概括
周围动脉疾病 (PAD) 的治疗方法在间歇性关节障碍 (IC) 和慢性肢体威胁性缺血 (CLTI) 之间有所不同. 对于CLTI患者来说,结果更糟糕,因此需要针对外围动脉疾病量身定制的内血管策略.
科学领域:
- 血管外科 血管外科
- 干预心脏病学 干预心脏病学
- 血管内干预 血管内干预
背景情况:
- 周围动脉疾病 (PAD) 呈现出不同的解剖分布,病变特征和治疗选择.
- 血管内干预是症状性PAD的主要治疗方式,包括间歇性关节障碍 (IC) 和慢性肢体威胁性缺血症 (CLTI).
研究的目的:
- 为了研究和比较用于PAD患者进行IC再血管化治疗的内血管器件与CLTI.
- 分析IC和CLTI患者群体之间的患者人口统计,病变特征和程序结果的差异.
主要方法:
- 在韩国,2019-2022年间,一个多中心注册表确定了736名PAD患者.
- 分析了接受内血管治疗的506名IC或CLTI患者的数据,检查了患者特征,目标病变和设备数据.
- 评估了甲状腺,股骨和膝盖以下病变的结果.
主要成果:
- 与IC患者相比,CLTI患者的糖尿病,膝下干预和多层次PAD的发病率较高.
- 常见IC患者更频繁地出现了大心血管病变,并接受了切除术.
- 虽然CLTI患者接受了更多的关节损伤支架,但CLTI组的初级通透性,截肢和死亡率明显更差.
结论:
- 在韩国IC和CLTI患有PAD患者的基线特征,病变复杂性,内血管方法和短期结果之间存在显著差异.
- 这些发现强调了基于PAD严重程度和患者表现的个性化内血管策略的需要.
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