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高频重复性跨脑磁刺激及其对慢性精神分裂症症状,认知和主观经验的影响:一项虚假控制研究

Lijun Liu¹, Lida Shi¹, Dongmei Xu¹

¹Department of Mental Rehabilitation, Hebei General Hospital for Veterans Affiliated to North China University of Science and Technology, Baoding City, China.

Noro psikiyatri arsivi

|June 13, 2024

概括

高频重复性横磁性刺激 (rTMS) 并没有改善慢性精神分裂症症状或认知能力. 然而,rTMS确实增强了患者的主观治疗体验,可能改善了合规性.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.

背景情况:

精神分裂症是一种慢性精神障碍,影响认知和日常功能.
重复性跨脑磁性刺激 (rTMS) 是一种新兴的神经调节技术.

研究的目的:

研究高频rTMS对精神分裂症症状,认知功能和主观患者体验的影响.
为了加深对TMS作为慢性精神分裂症治疗方法的理解.

主要方法:

一项随机对照试验,涉及33名慢性精神分裂症患者.
参与者被分配接受主动rTMS (n=17) 或假刺激 (n=16).
标准化尺度评估了症状,认知功能,洞察力和治疗后的主观经验.

主要成果:

在症状严重程度,认知表现或洞察力方面,在rTMS和假装组之间没有观察到统计学上显著的差异.
接受活性rTMS的患者报告了显著更多的积极主观体验和更好的整体治疗体验.

结论:

高频rTMS在改善核心症状,认知缺陷或慢性精神分裂症的洞察力方面没有表现出有效性.
与rTMS相关的增强的主观体验可能会积极影响治疗的坚持和遵守.

关键词:

认知功能认知功能负面症状负面症状积极的症状是积极的症状.重复的横性磁性刺激是重复性的.精神分裂症是一种精神分裂症.

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