概括
这项研究使用间接方法在摩洛哥确定了全血细胞计 (CBC) 的年龄和性别参考间隔. 结果显示,性别差异很小,但血小板和红细胞数量与年龄相关的变化.
科学领域:
- 临床实验室科学 临床实验室科学
- 血液学 血液学 血液学
- 人口健康 人口健康
背景情况:
- 参考间隔对于解释实验室测试和管理患者护理至关重要.
- 建立特定于当地人口的准确参考间隔是必不可少的.
- 这项研究重点关注完整血清 (CBC) 参数.
研究的目的:
- 确定摩洛哥人口中CBC参数的特定年龄和性别的参考间隔.
- 为了验证建立这些参考区间的间接方法.
- 将发现与现有的国际和教科书参考范围进行比较.
主要方法:
- 对15070名表面健康的成年人 (5,898名男性,10,172名女性) 的CBC数据进行了回顾性分析,年龄为18-90岁.
- 2018年1月至2020年2月期间从摩洛哥实验室信息系统收集的数据.
- 根据临床和实验室标准研究所 (CLSI) 的指导方针,使用非参数统计技术来计算参考限值.
主要成果:
- 对于大多数CBC参数,没有观察到临床上显著的基于性别的差异,血红蛋白 (HB),平均体质体积 (MCV),平均体质血红蛋白 (MCH) 和平均体质血红蛋白度 (MCHC) 的微小变化.
- 对大多数分析对象而言,与年龄相关的差异是最小的.
- 血小板计数 (PLT) 显示,随着年龄的增长,男性和女性的血小板数量都在持续下降. 红细胞计数 (RBC),血红素 (HCT) 和HB水平表现出与年龄相关的趋势,在女性中随着年龄的增长而增加,在男性中表现出更复杂的模式.
结论:
- 在采用适当的选择标准和统计工具时,间接方法是建立CBC参考区间的可行方法.
- 来自摩洛哥CBC的参考间隔不同于教科书和国际范围.
- 这些发现强调了特定人群参考间隔对于准确的临床解释的重要性.
相关概念视频
01:15Assessment of blood pressure in brachial artery(one-step method)
This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Prepare for the Procedure:
01:28Special considerations while measuring blood pressure
When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
01:10Pre-Procedural Guidelines for Assessing Blood Pressure
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.