儿童患有与人类口腔病毒1感染相关的塑性支气管炎
Zhang Fei-Zhou1, Huang Mei-Xia1, Tao Xiaofen1
1Department of Pulmonology, National Clinical Research Center for Child Health, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
人口口腔病毒1 (hBoV1) 可以引起儿童的塑性支气管炎 (PB). 支气管镜检查对于诊断和治疗这种气道阻塞至关重要,症状通常在干预后消失.
科学领域:
- 儿科呼吸系统医学 儿科呼吸系统医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 塑性支气管炎 (PB) 是一种严重的气道阻塞,由内源性物质异常积累引起.
- 它损害了肺呼吸,需要及时诊断和管理.
研究的目的:
- 要总结临床特征,诊断和治疗儿童的PB二次到人类口腔病毒1 (hBoV 1) 感染.
- 为改善儿童患者hBoV 1相关PB的早期检测.
主要方法:
- 追溯分析2021年1月至2024年1月期间诊断出PB和hBoV 1感染的六例儿科病例.
- 诊断方法包括支气管镜检查,甲基因组下一代测序和呼吸道病原体核酸检测.
主要成果:
- 所有六个孩子都出现了发烧,咳和喘息;高分辨率CT显示出和肺炎.
- 支气管镜检查证实了塑性支气管炎,并且在切除后得到了症状缓解.
- 病理学揭示了与非淋巴性PB一致的炎症性排泄.
结论:
- 患有hBoV 1感染的儿童持续出现的呼吸道症状可以怀疑PB.
- 支气管镜检查对于诊断和有效治疗塑性支气管炎至关重要.
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