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Updated: Jun 24, 2025

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
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Published on: August 13, 2012

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在CFTR功能丧失期间,DRA参与了林纳克洛提德刺激的二碳酸盐分泌

Jessica B Sarthi1, Annie M Trumbull1, Shayda M Abazari1

  • 1Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition; and.

JCI insight
|June 13, 2024
PubMed
概括

利纳克洛提德增强了十二指肠二碳酸盐分泌,这对于肠道保护和消化至关重要,即使囊性纤维化转膜导电调节器 (CFTR) 缺失. 这表明林纳克洛提德是囊性纤维化患者的潜在治疗方法.

关键词:
离子和水的上皮运输.胃肠病学 胃肠病学关酸环酸酶的使用方法

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