一个严重和长期的眼球水病例,没有系统性表现
Kevin Shan1, Lorena A Montalvo-Toledo, Amde Selassie Shifera
1Flaum Eye Institute, University of Rochester Medical Center, Rochester, NY.
Cornea
|June 13, 2024
概括
本病例报告详细介绍了一例罕见的严重眼球病毒 (mpox) 感染,没有全身症状. 及时的抗病毒治疗导致持续的眼睛炎症和病变的快速消失.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 病毒 (mpox) 的眼部表现不常见,特别是在没有系统性疾病的情况下.
- 严重的眼睛mopox可以导致严重的炎症,角膜并发症和视力受损.
研究的目的:
- 报告一个罕见的长期和严重的眼睛mopox感染病例.
- 要突出诊断挑战和治疗结果在一个患者与mopox相关的角膜炎和结膜炎没有系统性参与.
主要方法:
- 单一案例报告. 一个案例报告.
- 记录了临床表现,包括核酸放大测试 (NAAT) 在内的诊断工作以及治疗过程.
- 评估了眼科检查结果和对抗病毒治疗的反应.
主要成果:
- 一名60岁的男子出现了严重的眼部症状,包括结膜炎,眼病变和逐渐的外周性角膜炎,角膜变薄.
- 最初的类固醇和免疫抑制剂治疗提供了暂时的缓解,但症状复发.
- 在8个月后,mopox的诊断通过眼拭片上的NAATs得到证实;迅速启动全身tecovirimat,cidofovir和局部trifluridine导致眼部炎症和病变的快速消失.
结论:
- 眼睛mopox可以不典型地呈现严重的,视力威胁的眼睛表面疾病,而没有系统性表现.
- 早期诊断和及时启动抗病毒治疗对于管理严重的眼睛mopox和预防长期并发症至关重要.
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