在肉类包装工厂中发现的环境生物膜中,SARS-CoV-2的三角形变异仍然是可行的
Austin B Featherstone1, Arnold J T M Mathijssen2, Amanda Brown1
1Department of Animal Science, Texas A&M University, College Station, Texas, United States of America.
PloS one
|June 13, 2024
概括
在肉类包装厂的表面上,SARS-CoV-2 Delta 变异仍然是可行的,其中一些生物膜增加了病毒颗粒数量. 生物膜可以保护病毒免受消毒剂的侵害,从而促进病毒在这些环境中的流行.
科学领域:
- 环境微生物学环境微生物学
- 病毒学 病毒学
- 食品安全科学 食品安全科学
背景情况:
- 肉类包装厂中SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2) 的流行程度表明环境因素有助于其持续存在.
- 生物膜,表面上的微生物群落,在工业环境中很常见,可以容纳病原体.
研究的目的:
- 研究在肉类包装厂的典型材料上形成的生物膜中SARS-CoV-2Delta变种的生存能力和传染性.
- 了解SARS-CoV-2与环境生物膜之间的相互作用及其对病毒生存和食品安全的影响.
主要方法:
- 在不钢,PVC和陶上使用肉类包装厂排水样本开发混合物种生物膜.
- 用SARS-CoV-2Delta变种注射生物膜,并在7°C化5天.
- 使用斑块检测和定量聚合酶链反应 (qPCR) 评估病毒生存能力.
主要成果:
- 在所有经过测试的表面上,无论有没有生物膜,SARS-CoV-2的Delta变异仍然是可行的.
- 特定的生物膜 (植物B,植物C) 影响了病毒活力,有时会增加传染性病毒颗粒数量 (1.81-4.57倍).
- SARS-CoV-2 德尔塔变种增加了生物膜生物体积,引发了人们对与食物传播病原体的潜在共存的担忧.
结论:
- 肉类包装厂中的环境生物膜可以支持SARS-CoV-2Delta变种的生存能力,并可能增强其生存能力.
- 复杂的病毒-生物膜相互作用,受生物膜组成的影响,影响病毒的持久性.
- 生物膜可以保护SARS-CoV-2免受消毒,有助于其在这些设施中的持续存在.
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