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过量的风险 过量的风险
Seo Young Sohn1, Kosuke Inoue2,3, Connie M Rhee4,5
1Division of Endocrinology, Department of Internal Medicine, Myongji Hospital, Hanyang University College of Medicine, Goyang 10475, South Korea.
Endocrine reviews
|June 13, 2024
概括
过度的摄入,特别是来自有的对比剂,可以导致敏感个体的甲状腺功能障碍. 需要进一步的研究来确定安全的摄入限值,特别是对于高风险人群.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 放射学 放射学是一门学科.
背景情况:
- 对于甲状腺激素的合成至关重要.
- 身体利用甲状腺毛囊细胞内的酸循环来产生激素.
- 来源包括饮食,补充剂,阿米奥达龙和含的对比介质.
研究的目的:
- 审查过多的摄入量与甲状腺功能障碍之间的关联.
- 专注于含的对比介质作为过量的重要来源.
- 总结脆弱人群中的风险,并讨论潜在的非甲状腺健康影响.
主要方法:
- 关于状态评估的文献综述 (尿中的,甲状腺蛋白,TSH,甲状腺体体积).
- 在诱导的甲状腺功能障碍中分析沃尔夫-柴科夫和约德-贝塞多现象.
- 检查查和监测对比引起的甲状腺功能障碍的指导方针.
主要成果:
- 过度的摄入,特别是来自对比介质的摄入,可以在易受影响的个体中引发甲状腺功能低下或甲状腺功能增强症.
- 易受伤害的群体面临过量增加的风险.
- 与过多的相关的潜在的长期非甲状腺健康风险需要进一步调查.
结论:
- 过度暴露于,特别是通过含的对比剂,会造成甲状腺功能障碍的风险.
- 目前的指导方针涉及对比引起的甲状腺功能障碍的查和监测.
- 需要更多的数据来确定高风险群体安全的摄入量上限.
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