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相关概念视频

Panic Disorder01:27

Panic Disorder

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Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
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Functional Brain Systems: Limbic System01:15

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The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
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Borderline Personality Disorder01:25

Borderline Personality Disorder

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Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
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Introduction to Psychological Disorders01:19

Introduction to Psychological Disorders

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Abnormal behavior, often referred to as mental illness, results from changes in brain function that influence thought patterns, behaviors, and social interactions. Psychologists and psychiatrists typically assess abnormal behavior using three primary criteria: deviance, maladaptation, and personal distress, particularly when these traits persist over long periods.
Deviant Behavior
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Personality Disorders: Paranoid and Schizoid01:22

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Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
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Social Anxiety Disorder01:28

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Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
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在恐慌障碍中异常的insula网络特征.

Linlin You1, Wenhao Jiang2, Taipeng Sun3

  • 1Nanjing Medical University, Nanjing, China. Department of Psychosomatics and Psychiatry, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
|June 13, 2024
PubMed
概括
此摘要是机器生成的。

恐慌症 (PD) 与异常的大脑网络有关,特别是在岛内功能连接 (FC) 和节点效率 (Ne) 的降低. 这些发现表明,信息整合障碍有助于PD症状.

关键词:
恐慌失调是一种恐慌失调.功能连接连接功能连接岛屿皮层的岛屿皮层.模块化网络是一个模块化网络.拓学的属性 拓学的属性

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科学领域:

  • 神经科学是一个神经科学.
  • 精神病学是一个精神病学.
  • 医疗成像医学成像

背景情况:

  • 恐慌失调 (PD) 是一种普遍且残疾的疾病,其特征是经常出现的恐慌发作.
  • 在PD中,情绪和行为缺陷与功能连接 (FC) 和大脑中的网络异常有关.

研究的目的:

  • 在患有恐慌障碍 (PD) 的人群中调查全脑功能连接 (FC),模块化网络和图形理论属性.
  • 探索广泛的网络配置文件,并确定PD中大脑网络组织中的异常.

主要方法:

  • 功能磁共振成像 (fMRI) 数据分析了82名患有PD的受试者和97名健康对照者的数据.
  • 评估了160个大脑区域之间的内在FC,以及6个网络内部和15个网络间的FC.
  • 使用图形理论指标分析了大脑网络的拓性质.

主要成果:

  • 患有PD的患者在包括胰岛,额叶皮质,后带皮质 (PCC),小脑和皮质在内的区域表现出改变的FC.
  • 在传感运动网络 (SMN) 内以及在SMN和尾网络 (OCN) 之间观察到减少的连接性.
  • 在PD症状严重程度和节点效率降低 (Ne) 和岛内FC之间发现了显著的相关性.

结论:

  • 患有PD的个体表现出异常的功能性脑网络.
  • 在胰岛内降低FC和Ne是PD的突出发现.
  • 大脑信息整合的功能障碍似乎在PD的病理生理学中发挥着关键作用.