在相关闭条件下,在巨电压束辐射期间,形束计算断层成像的性能
Hiraku Iramina1, Mitsuhiro Nakamura2, Makoto Sasaki3
1Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
概括
在肺部立体体辐射疗法期间的内辐射成像允许目标定位. 虽然图像质量需要改进,但封闭千伏 (kV) 成像成功可视化了目标.
科学领域:
- 医学物理 医学物理
- 放射治疗技术 放射治疗技术
- 图像指导 图像指导
背景情况:
- 精确的目标定位对于肺部立体体辐射疗法 (SBRT) 至关重要.
- 辐射内成像的目的是在光束传递过程中获得目标位置.
- 照射期间的相隔成像是一种新的方法,可以提高精度.
研究的目的:
- 在相隔条件下,在光束照射 (辐射内照射成像) 期间评估千伏 (kV) 成像的性能.
- 使用呼吸运动幻影来评估图像质量和目标检测能力.
主要方法:
- 利用Catphan 504和QUASAR幻影用于图像质量和目标检测性评估.
- 采用了一个TrueBeam STx linac,具有开发者模式,125kVp和1.2 mAs/投影.
- 研究了各种兆电压 (MV) 的X射线束能量,场尺寸和率,用于辐射内成像,包括代重建 (IR).
主要成果:
- 在封闭条件下的内辐射圆束CT (CBCT) 图像显示,根平均平方误差 (RMSE) 为50-230 HU,噪声水平为15-35 HU.
- 较低的率增加了RMSE和噪声,但代重建 (IR) 改善了这些指标.
- 带有IR的约7fps实现了对比度与噪声比率 (CNR),相当于没有IR的15fps.
- 目标在所有封闭式内辐射CBCT图像上始终可见.
结论:
- 内辐射CBCT图像显示出良好的视觉目标检测能力.
- 为了最佳的临床实施,需要进一步提高图像质量.
- 阶段关口内辐射成像显示,有望在肺SBRT中准确地定位目标.
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