pH对大豆乳清蛋白-阿拉比克乳液输送系统对黄素的影响:乳化,稳定性和消化性能
Jia Cao1, Xiaohong Tong2, Xinru Cao1
1College of Food Science, Northeast Agricultural University, Harbin 150030, China.
Food chemistry
|June 13, 2024
概括
一个新的大豆乳清蛋白乳液系统与阿拉伯糖有效地提供黄素 (CUR). 这种新的输送增强了CUR的稳定性和生物可用性,为营养素提供了有前途的载体.
科学领域:
- 食品科学 食品科学 食品科学
- 生物材料科学 生物材料科学
- 营养科学 营养科学
背景情况:
- 黄素 (CUR) 具有有益的特性,但其稳定性和生物可用性不佳.
- 开发有效的传递系统对于增强CUR的治疗潜力至关重要.
- 豆蛋白 (SWP) 和阿拉伯糖 (GA) 是天然的生物聚合物,具有封装应用的潜力.
研究的目的:
- 开发一种新的黄素 (CUR) 输送系统,使用基于大豆乳清蛋白 (SWP) 的乳液.
- 通过调整pH值和修改阿拉伯 (GA) 来提高CUR的稳定性和生物可访问性.
- 研究静电相互作用和界面特性对CUR封装和输送的影响.
主要方法:
- 用GA和pH调整修改的SWP基乳液的制造.
- 界面特性,乳化能力和CUR封装效率的表征.
- 在热,紫外线,氧化和储存条件下评估CUR稳定性.
- 通过模拟胃和肠道消化对CUR生物可访问性的评估.
主要成果:
- 在pH 6.0下,SWP-GA乳液系统显示出显著增强的乳化特性和CUR封装效率.
- CUR封装效率达到了90.15%±0.67%,接口面积为870.53±3.22 m2/g.
- 观察到CUR的热,紫外线,氧化和储存稳定性的显著改善 (P <0.05).
- 该系统在pH 6.0下实现了69.12% ± 0.28%的高CUR生物可访问性,GA在胃消化过程中保护CUR,并在肠道消化过程中促进释放.
结论:
- 开发的SWP-GA-CUR乳液输送系统代表了黄素的新且有效的载体.
- SWP和GA之间的pH介导的静电相互作用是实现稳定的乳液和高封装的关键.
- 这种输送系统显著提高了CUR的稳定性和生物可用性,为改善营养物质输送应用铺平了道路.
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