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在胰腺移植后探索移植胰腺炎的定义:一个范围审查
Stefano Partelli1, Valentina Andreasi1, Valentina Tomajer2
1Pancreatic and Transplant Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.
Transplantation reviews (Orlando, Fla.)
|June 13, 2024
概括
在胰腺移植 (PT) 后的移植胰腺炎 (GP) 缺乏标准定义. 这次审查发现了20个不同的定义,强调需要达成共识,以改善PT的患者护理和研究.
科学领域:
- 移植免疫学 移植免疫学
- 胃肠病学 胃肠病学
- 手术病理学的外科病理学
背景情况:
- 移植胰腺炎 (GP) 是胰腺移植 (PT) 后的一种严重并发症.
- 缺乏普遍接受的GP定义阻碍了一致的诊断和管理.
- 现有的定义在标准和应用方面存在很大差异.
研究的目的:
- 系统地审查和概述科学文献中报道的移植性胰腺炎 (GP) 的各种定义.
- 确定GP的不同定义中使用的标准.
- 为了强调在GP定义上缺乏共识.
主要方法:
- 使用了一个范围审查方法.
- 在 MEDLINE, Web of Science 和 Embase 数据库中进行文献搜索.
- 包括前性和后性研究,报告了GP的定义.
主要成果:
- 在20项研究中,鉴定出了20种截然不同的胰腺移植炎 (GP) 定义.
- 定义使用了临床,生化,放射学和病理学标准的组合.
- 全科医生发病率在不同研究中差异很大,从0%到87%不等.
结论:
- 对移植性胰腺炎 (GP) 缺乏普遍接受的定义.
- 关于应该构成GP定义的基础的标准,没有达成共识.
- 未来的研究必须优先考虑制定和验证标准化GP定义,以改善临床实践和研究成果.
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