的年代型变异性和临床意义:范围审查
Lucas Lima Najar1, Roberto Pereira Santos2, Nancy Foldvary-Schaefer3
1Fellow - Graduate Program in Psychiatry and Mental Health of the Institute of Psychiatry - PROPSAM-IPUB: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Epilepsy & behavior : E&B
|June 13, 2024
概括
患有 (PWE) 的人通常具有中间的时刻型. 成年PWE倾向于早晨性,而儿童则表现出可变的模式,一般性与晚上性有关.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 时间生物学 时间生物学
背景情况:
- 时刻型,或日常活动-睡眠偏好,在中没有得到充分的研究.
- 了解患者 (PWE) 的时间型可能会影响管理.
研究的目的:
- 为了确定PWE中常见的年代型特征.
- 探索时间型和发作控制之间的潜在联系.
主要方法:
- 一项对11项大规模研究 (2010-2023) 的范围审查.
- 包括1,167名PWE和4,657名对照对象.
主要成果:
- 在PWE中,主要表现出中间的时刻型.
- 成年人倾向于早晨; 儿科时间型是可变的.
- 泛性与晚间时间型相关;焦点的数据有限.
- 关于成年人时刻型和控制的结果存在矛盾.
- 时间型与特定抗发作药物 (ASM) 治疗的关系没有研究.
结论:
- 大多数PWE具有中间的年代型,与年龄相关的变化 (儿童的变量,成人以早晨为导向).
- 泛性与晚间时间类型有关.
- 用更大的PWE样本进行进一步的研究对于了解时间型在的结果,控制和ASM治疗中的作用至关重要.
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